The National Institutes of Health (NIH) and the Agency for Healthcare Research and Quality (AHRQ) have issued a notice, clarifying their resubmission policy.

NIH has summarized the updates as follows:

• Only a single resubmission (A1) of an original application (A0) will be accepted
• An A0 application may be submitted following an unsuccessful A0 or A1 application, with a few exceptions
• What happens when switching FOAs between the A0 and A1 applications
• Generally a change of activity code (e.g., R01) between the A0 and A1 is not allowed, with one exception

For details: NIH Article, NIH Policy Notice.